Thursday, November 6, 2014
Posted By: Nomonanoto Sidama | At: 11/06/2014 05:59:00 AM
Diabetes mellitus coexists at a greater frequency with hypertension, obesity, central obesity, dyslipedemia and proteinuria and that markedly increases the risk of atherosclerotic disease. A study was done for a period of four months in Sidama Zone, Southern Ethiopia to compare the prevalence of atherosclerotic risk factors between diabetic and non diabetic general population. One hundred ninety nine diabetic cases were selected from two hospitals diabetic clinics and 195 non diabetics subjects were selected from urban and rural areas. The general prevalence of hypertension in the entire study population was 18.8%, with 26.1% in diabetics and 10.2% in non diabetics. Multivariate logistic regression showed that hypertension, central obesity, overweight and obesity, and ethnicity had strong association with possibility of diabetes mellitus. The reason for possible racial difference to cardiovascular risk factors and population awareness to these factors should be studied. [Ethiop. J. Health Dev. 2010;24(2):145-147]
Posted By: Nomonanoto Sidama | At: 11/06/2014 05:49:00 AM
The effects of prenatal Zinc Deficiency (ZD) and Vitamin A Deficiency (VAD) on birthweight are controversial and their interaction has not been investigated.
To assess the independent and interaction effects of prenatal zinc and vitamin A deficiencies on birthweight in rural Sidama, Southern Ethiopia.
A community-based prospective cohort study design was employed. Six hundred fifty pregnant women in their second or third trimester were randomly selected and their serum zinc and retinol concentrations were determined. About 575 subjects were successfully followed until delivery and birthweight was measured within 72 hours after delivery. The association between the exposures and birthweight was examined using log-binomial and liner regression analyses. Potential interaction between ZD and VAD was examined using Synergy Index (SI).
The mean birthweight (± standard deviation) was 2896 g (±423). About 16.5% (95% CI: 13.5–19.6%) of the babies had Low Birthweight (LBW). Prenatal ZD and VAD were not significantly associated to LBW with Adjusted Relative Risk (ARR) of 1.25 (95 CI: 0.86–1.82) and 1.27 (95% CI: 0.86–1.87), respectively. Stratified analysis on the basis of gestational trimester showed that the occurrence of the deficiencies neither in the second nor third trimester were associated to LBW. The deficiencies did not show synergetic interaction in causing LBW [SI = 1.04 (95% CI: 0.17–6.28)]. Important risk factors of LBW were maternal illiteracy [RR = 1.80 (95% CI: 1.11–2.93)], female sex of the newborn [RR = 1.79 (95% CI: 1.19–2.67)], primiparity [RR = 1.16 (95% CI: 1.02–1.35)], short maternal stature [RR = 1.63 (95% CI: 1.06–2.51)] and maternal thinness [RR = 1.52 (95% CI: 1.03–2.25)]. In the linear regression model, elevated CRP was also negatively associated to birthweight.
LBW is of public health significance in the locality. The study did not witness any independent or interaction effect of prenatal ZD and VAD on birthweight.
Read more at: www.plosone.org
Posted By: Nomonanoto Sidama | At: 11/06/2014 05:33:00 AM
Posted By: Nomonanoto Sidama | At: 11/06/2014 05:26:00 AM