ABSTRACT Quantifying the hydrologic response of land use/land cover change (LULCC) is of paramount importance to improve land management. This study was carried out to analyze the effect of LULCC on water quality and quantity. LULCC of the watershed in 1986, 1999 and 2011 was analyzed from Landsat satellite images using supervised classification. Time series and point data were collected from the upper and lower sections of Wedesa, Wesha and Hallo Rivers . Water quality parameters (turbidity, suspended solid (SS), total dissolved solid (TDS), pH, electric conductivity (EC), total organic carbon (TOC), ammonia, nitrate and phosphate) were analyzed in the laboratory. A considerable decline in forest and an increase in woodland were observed in the watershed during the indicated periods. Turbidity, SS, TDS and EC were significantly higher ( P < 0.05) in the lower section of the rivers compared to the upper ones. Ammonia, nitrate and phosphate were higher in the lower section o